Earlier in the month the latest updates were released for .NET framework. Since then multiple customers have mentioned that this has caused issues for them trying to open .NET applications. These are specific applications that use the COM component and run with restricted permissions. For now Microsoft have stopped distributing this update and are looking into a fix. Microsoft recommend that if you have seen these issues on your machine then as a current workaround you should remove the latest updates or if you aren’t seeing issues then there is no need to remove them.